General Cell Lines and Cell Cultures
ATCC Merck Pneumococcal polysaccharide powder Type 9 (d9N) 200mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae.Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
ATCC Lactiplantibacillus plantarum
Lactiplantibacillus plantarum strain [BUCSAV 248, NCDO 343, NCIB 7220, NCIB 8184, NCTC 7220] is a whole-genome sequenced bacterium that was isolated in England from Sauerkraut. This strain produces acetylcholine.
ATCC Human respiratory; syncytial virus; Strain: 18537; RNA
Viral nucleic acids, including viral genomic RNA, in total RNA isolated from Hep-2 cells (ATCC CCL-23) infected with Human respiratory syncytial virus strain 18537 (ATCC VR-1580). Virus and host cells are also available through the ATCC catalog. This product was prepared using methods known to inactivate viruses. RNA isolated from virally infected cells can be used for RT-PCR and other molecular virology applications.
ATCC Human Coxsackievirus B1; Strain: Conn-5
Human Coxsackievirus B1 strain Conn-5 is propagated in LLC-MK2 Derivative cells (ATCC CCL-7.1). This strain was isolated in 1948 from the stool of a human patient with aseptic meningitis in Connecticut, US, and was deposited by the Yale University School of Medicine.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Stomach, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Candida orthopsilosis; MCO457
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
Eurofins Discoverx ChemiScreen LPA2 Lysophospholipid Receptor Stable Cell Line, 2 vials. (HTS207C)
The ChemiScreen LPA2 Lysophospholipid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. LPA) based activation of LPAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses LPAR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of LPAR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay S1P4 Lysophospholipid Receptor Frozen Cells, 2 Vials of Cells. (HTS192RTA)
The Ready-to-Assay S1P4 Lysophospholipid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. S1P) based activation of S1PR4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses S1PR4 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of S1PR4, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen MRGPRD Receptor Membrane Preparation, 1 vial. (HTS206M)
The ChemiScreen MRGPRD Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of MRGPRD surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen Ghrelin Receptor Stable Cell Line, 2 vials. (HTS187C)
The ChemiScreen Ghrelin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ghrelin) based activation of GHSR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GHSR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of GHSR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay Y4 Neuropeptide Y Receptor Frozen Cells, 2 Vials of Cells. (HTS204RTA)
The Ready-to-Assay Y4 Neuropeptide Y Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. peptide YY) based activation of NPY4R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses NPY4R alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of NPY4R, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen α1D Adrenergic Receptor with N-terminal truncation Membrane Preparation, 1 vial. (HTS216M)
The ChemiScreen α1D Adrenergic Receptor with N-terminal truncation Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRA1D (82-572) surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen GPR103/Peptide P518 Receptor Stable Cell Line, 2 vials. (HTS189C)
The ChemiScreen GPR103/Peptide P518 Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. QRFP neuropeptides) based activation of QRFPR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses QRFPR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of QRFPR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.